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Do not use in individuals with hypersensitivity to pyridoxine or any ingredient in the formulation

- Stable gastric pentadecapeptide BPC 157 heals rat colovesical fistula - Stable gastric pentadecapeptide BPC 157 heals rectovaginal fistula in rats - Gastric pentadecapeptide BPC 157 and short bowel syndrome in rats - ncbi.nlm.nih.gov/pubmed/19093208 Cytoprotective Mechanism of the Novel Gastric Peptide BPC157 in Gastrointestinal Tract and Cultured Enteric Neurons and Glial Cells - Neuroscience Bulletin volume 35, pages167170 (2019) Esophagogastric anastomosis in rats: Improved healing by BPC 157 and L-arginine, aggravated by L-NAME - Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats - Stable Gastric Pentadecapeptide BPC 157 and Wound Healing (2021) -

However, numerous studies indicate that individuals with ME/CFS experience increased intestinal permeability, supporting the theory that Gram-negative bacterial endotoxins, also known as LPS, may enter the mesenteric lymph nodes and the blood stream through the loosening of tight-junction proteins (e.g., Zonulin), triggering an immune response and resulting in systemic inflammation [10, 21, 24, 39,40,41,42]

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