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However, it took another 26 years to identify and sequence the 41-amino acid peptide that plays a pivotal role in the stress-related pituitary release of ACTH and -endorphin (Vale et al., 1981

We suppose that inconsistent results concerning glutathione concentrations in old rats, which were provided by various authors, may by a consequence of subclinical disease which was not taken into account by researchers

Additional experiments conducted on various mammalian cells have indicated that treatment with the purine antimetabolite 6-TG can cause DNA single- and double-strand breaks, as well as chromosomal damage [49, 50]

When the desensitized GSH I-encoding gene gshA * was cloned, the activity of the mutant GSH I increased tenfold compared with the wild type enzyme