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They have been extensively studied in large-scale human clinical trials, with robust safety data spanning over a decade

[DOI] [PubMed] [Google Scholar] 187.Hatch HW, Bergonzo C, Blanco MA, Yuan G, Grudinin S, Lund M, Curtis JE, Grishaev AV, Liu Y, Shen VK

This method reduces contamination risk in extended research projects

In animal studies, subcutaneous injection has been shown to significantly increase slow-wave (delta) sleep in cats at 120 nmol/kg, promoting deep sleep and enhancing overall rest