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Moreover, incorporating polyphenols into the diet of adults and the elderly can enhance overall health, diminish the hazard of chronic disorders, and promote cardiovascular well-being (535, 536)

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Contraindications and clinical precautions include: Medullary thyroid carcinoma (MTC): Cagrilintide is contraindicated in individuals with a personal or family history of MTC due to its structural similarity to calcitonin, which may theoretically influence C-cell activity

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p53, a classical tumor suppressor gene, inhibits the uptake of cystine by System Xc- through downregulation of SLC7A11 expression, leading to a decrease in the antioxidant capacity of cells

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