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However, for the subgroup of studies in which patients received IV GLN and were on EN alone [23, 33], GLN supplementation was associated with a trend towards a reduction in infectious complications (RR 0.68, 95% CI 0.45, 1.05, P = 0.08, heterogeneity I 2 = 0%

The amount of additional processing effects on the brain and its dissociation from neurofeedback effects, the amount of helpful reward processes for the learner, as well as the clearness and ease to understand its usage are largely unknown factors