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Description

ROS can attack proteins to form carbonyls and react with nitrogen species and tyrosine to form nitrotyrosine

10.1002/mnfr.201200721 303

The four-pathway model therefore targets appetite (GLP-1 and amylin through separate neuronal circuits), fat metabolism (GIP and glucagon), energy expenditure (glucagon primarily), and glucose homeostasis (GLP-1, GIP, and amylin all contribute through different mechanisms)