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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies

548 Additionally, a medication review to adjust or discontinue medications that may impair cognition or balance is recommended to decrease fall risk

If youre having trouble sleeping, a B12 Vitamin Shot can help regulate your sleeping patterns by controlling your melatonin levels

Taking extra B12 when your levels are already normal is not known to add energy or other benefits