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DOI: 10.1023/A:1025493705728 Korkushko OV, Khavinson VKh, Shatilo VB, Antonyk-Sheglova IA

166 RuzzaP.RosatoA.RossiC

The SARS-CoV-2 infection initiates complex human host-pathogen interactions and alters mitochondrial function with significant disruption of glycolysis/TCA cycle (Warburg effect), affecting several metabolic pathways of amino acid (AA), fatty acid (FA), nucleotide, and antioxidant synthesis 139,140