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Results: Our search yielded 1375 studies, of which 39 studies with a combined 2257 subjects were included in the analysis

Vitamin B12 is vital for human life due to its role in making red blood cells and supporting the function of the brain and nerves

Boosts appetite: Adequate levels of B12 can promote a healthy appetite in dogs

Mechanism of Action Nitric Oxide Synthase Pathway : L-citrulline works by converting to arginine through the urea cycle via argininosuccinate synthase and argininosuccinate lyase enzymes, then interacting with nitric oxide synthase (NOS) enzymes to generate nitric oxide and support the relaxation of blood vessel smooth muscle