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Tomita K, Smith PM, Takayama M, Pan C, Shen S, Wang X, Wang XS, Williams LA, Arvide EM, To C, Rajaram R, Mitchell KG, Rice DC, Hofstetter W, Antonoff MB , Mehran RJ, Vaporciyan A, Walsh GL, Maxwell JE, Snyder RA, Kim MP, Tzeng CW, Mansfield PF, Swisher SS, Lee J, Badgwell BD, Katz M, Ikoma N

The above results demonstrated that the engineered strain MY-EcN successfully expresses the MY protein, which is selectively cleaved in the intestinal inflammatory microenvironment to yield the anti-inflammatory peptide KPV

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About one-half of these patients show an associated endocrinopathy such as autoimmune thyroiditis, Addisons disease, or hypoparathyroidism