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At the local level, the asthma-related changes include disturbances in the balance of Th1/Th2 pro- and anti-inflammatory cytokines, an increased cellular influx into the bronchi, chronic oxidative stress, and airway hyperreactivity

In some cases, the HDAC inhibitors could play a key role in pathogenesis of the neurodegenerative disease while in others these may act as feasible therapeutics for neurodegenerative disease

Hepatology 69 , 343358 (2019)

Vitamin B 12 is crucial for neurologic function, red blood cell production, and DNA synthesis, and is a cofactor for three major reactions: the conversion of methylmalonic acid to succinyl coenzyme A