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These findings highlight the potential of dual CYP17A1 and HDAC6 inhibition as a promising strategy to overcome resistance in GBM therapy, offering a new avenue for more effective treatments

Wang D, Zheng J, Hu Q, Zhao C, Chen Q, Shi P, Chen Q, Zou Y, Zou D, Liu Q, Pei J, Wu X, Gao X, Ren J, Lin Z (2020) Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis

The results show the role of cellcell interaction and intracellular NRF2-YAP signaling pathway in determining ferroptosis and show that malignant mutations in the NRF2-YAP signaling pathway can predict the response of cancer cells to future induction therapy for ferroptosis [72]

While thrombocytopenia is known to correlate with severity of portal hypertension and likelihood of variceal bleeding independent of MELD, its correlation with ascites pressure has not been studied