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Improved drug delivery methods Improved drug delivery mechanisms may also increase the potency of KPV and allow it to better resist degradation

Avoid heat, humidity, and direct sunlight

compositions according to the invention having the above-described preferred dissolution profile, include compositions with any of the following features: first coating comprising HPMC (such as, e.g., Methocel LV), followed by a second coating (which is exterior to the first coating) which is a pH dependent enteric coating (such as, e.g., Eudragit L30 D-55, Eudragit L100, or Eudragit S100), wherein the first coating preferably has a coating thickness between 200 pm and 700 pm (more preferably between 300 and 600 pm)

Because tolerability has not been quantified in humans, there is no evidence-based safe concentration or frequency to point to