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H1-Blockers and H2-blockers such as diphenhydramine (Benadryl) and Cimetidine (Tagamet) Corticosteroids such as cortisone, hydrocortisone, prednisone Omalizumab (Xolair) Leukotriene antagonists such as Montelukast Anaphylaxis Epinephrine (EpiPen) H1-Blockers and H2-blockers such as diphenhydramine (Benadryl) and Cimetidine (Tagamet) Corticosteroids such as cortisone, hydrocortisone, prednisone Omalizumab (Xolair) Naso-ocular - Nasal stuffiness, nasal swelling, runny nose H1-blockers including topical such as Olopatadine and Doxepin cream Topical corticosteroids such as hydrocortisone cream Topical formulations of Cromolyn sodium While certain medications can help relieve the symptoms of Mast Cell Activation Syndrome (MCAS), the inactive ingredients or fillers in these medications can sometimes trigger episodes

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Never stop prescribed B12 treatment without consulting your doctor, even if levels are elevated