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Antibiotic therapy and treatment failure in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease

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In the liver, it has a G of 17.6 kJ/mol (4.21 kcal/mol), and it is highly allosterically regulated

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This cascade activates caspase-8 and downstream caspase-3 (Takahashi et al., 1999), leading to DNA fragmentation and keratinocyte apoptosis (Simon et al., 2006)

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