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AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway

HGF heptocyte growth factor MSP macrophage stimulating protein the AnglV analog Norleual which is a potent inhibitor of the HGF/Met system, was shown to bind to HGF and block its dimerization (Kawas et al, 2011)

In a frequently cited series of experiments, tendons and ligaments were transected or crushed and then observed through the healing process with and without BPC-157 administration

Biologically active doses of HGF (10 ng/ml), Dihexa and Nlel -AnglV (10 "12 M) produced a significant effect over control treated spines (mean S.E.M