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The peptide suppresses pro-inflammatory cytokines including TNF-, IL-6, and TGF-, which are key drivers of chronic low-grade inflammation (inflammaging) in older skin

Moreover, injecting plain water into the bloodstream can be dangerous: without solutes, it is not isotonic to human blood and can cause red blood cells to burst (hemolysis)

PMID 29061763

Studies in mice demonstrated that a short course of MOTS-c treatment completely reversed age-related insulin resistance in old muscles after one week of MOTS-c administration, older mices muscles responded to insulin as effectively as those of much younger mice