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Although there are a large number of in vitro and in vivo studies investigating the mechanism of hypoxia-induced renal tubular damage, due to the lack of non-invasive means, there are few clinical studies that have evaluated renal hypoxia in detail

Probiotic and resveratrol normalize GLP-1 levels and oxidative stress in the intestine of diabetic rats

doi: 10.1093/infdis/jiz517 146 Caire-BrandliIPapadopoulosAMalagaWMaraisDCanaanSThiloLet al

3.3 GLT-1 is Degraded through Multiple Degradation Pathways following OGD To determine the post-endocytic processing of internalized GLT-1 following OGD, cultures were treated with proteasomal or lysosomal pathway inhibitors (MG-132 and Bafilomycin, respectively), after 2 h OGD (Figure 3A)