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The final Clc model comprised residues T 132 Q 480 , C-terminal tag residues A I A H H H H, one tentative pentaglycine, one diethylene glycol molecule, a sulphate ion, a chloride ion, a Tris molecule, a glycerol molecule, and 185 solvent molecules

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in combination with cisplatin for the initial treatment of patients with locally advanced or metastatic, non-squamous, non-small cell lung cancer (NSCLC)