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Furthermore, the uniform concentration profile across the bloodstream minimizes spatial variability, thereby avoiding the sampling-dependent gradients that frequently complicate ISF-based sensing modalities

Although reference ranges vary between laboratories, evidence suggests that disease risk begins to increase well before homocysteine reaches the traditional upper limit of 15 mol/L

Helps boost immune function by supporting white blood cell production

Both families of enzymes use NADP + as cofactors to perform reversible reactions, where isocitrate is oxidatively decarboxylated to alpha-ketoglutarate and generates one NADPH per reaction