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Because the production of anti-drug antibodies (ADAs) against biotherapeutics can have detrimental effects on drug safety, efficacy, and pharmacokinetics, immunogenicity an important factor in the toxicity profile of biotherapeutic proteins 16

This was a randomized, controlled trial that questioned the safety of current selenium upper tolerable intake limits

Dual faces of mitophagy in tumor initiation and progression Oncogenic KRAS mutation plays critical roles in the initiation and maintenance of PDAC progression and is associated with alterations in mitochondrial morphology and function

10.1002/bies.202400004