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Escherichia coli has been implicated in the metastasis of colorectal cancer to the liver, as it disrupts the gut vascular barrier, translocates to the liver, and fosters pre-metastatic niche formation

It is also worth investigating whether betaine deficiency is associated with the pathogenesis or with the severity of the above diseases

Long-chain FAOD (LC-FAOD) should be considered in any patient with cardiomyopathy, especially a new and acute onset

In addition to haemodynamic overload, uraemic toxin accumulation and altered ion homeostasis, which are known to underlie left ventricular hypertrophy in CKD and drive cardiac dysfunction, we examine the role of myocardial metabolic remodelling in CKD