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Indeed, evidence suggests that the clearance of TPO-Ab seems to occur in parallel with other immunologic mediators such as interferon-, TNF-, interleukin-1, and interleukin-2, as well as C-reactive protein (54, 55) which might explain the benefit of the complete removal of the antigenic tissue via total thyroidectomy

A: While this study focused on Huppke-Brendel Syndrome, many neurodegenerative diseases (like Alzheimers and Parkinsons) are characterized by misfolded proteins

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