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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Challberg MD

Although not significant, an increase in regulatory T-cells by 380% was detected

Mayxay M, Khanthavong M, Lindegardh N, Keola S, Barends M, et al

Unlike direct NAD+ infusions , which can sometimes cause side effects such as chest tightness, flushing, headaches, and an increased heart rate , Niagen is generally well tolerated with fewer reported discomforts