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In particular, regulators of membrane fluidity, cholesterol and sphingomyelin, increased significantly during gametocyte maturation (Tran et al., 2016)

IBB associates primarily with the C-terminal region III (HEATs 719), whereas Ran-GTP binds to the N-terminal arch comprising HEATs 113, validating previous mutagenesis studies 16 , with some overlap in HEAT 13