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1 ) : Control group Rats received intraperitoneal (i.p.) injections of a 0.9% saline solution (2.5 ml/kg) for 28 consecutive days

Direct answer: Weight loss is maintained during use, but stopping Semaglutide often leads to weight regain

As we did not observe the aforementioned locale selectivity for this parameter, we can only assume that the substances responsible for that particular behaviour work upon somewhat restricted pathways