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Resveratrol, with its anti-obesity effects and reduction of pro-inflammatory cytokines (TNF- and IL-6), has been found to reduce the expression of lipogenic genes (PPAR, C/EBP, FAS, and aP2) [110]

Further, in vivo studies using animal models (mice and rabbit) were done by injecting T4 either along with the application of rAAV.AKT-dn or inhibition of Rho/PI3K/AKT pathways

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The International Recommendations for the Management of Adults Treated With Ketogenic Diet Therapies noted that the majority of adult clinics check carnitine levels at baseline and at 1 year (21)