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detection: 0.5% 5-mC per 100 ng DNA

Start by considering your personal cancer history

However, a number of observations suggest that several cell types may be involved

In the catalytic hydrolysis of glutamine, Ser286 at the active site of the GLS1 enzyme carries out a nucleophilic attack on the acyl carbon of glutamine, and the subsequent proton transfer of Tyr466 promotes the hydrolysis reaction