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Emerging evidence indicates that mitochondrial dysfunction is closely associated with pathogenesis of sporadic and familial PD

Liesveld JL, Abboud CN, Looney RJ, Ryan DH, Brennan JK The Journal of immunology : official journal of the American Association of Immunologists

Since the Fgf15 ile-/- mice had a larger BA pool size and maintained higher serum concentrations of BAs post-SGx, the improved metabolic effects associated with SGx may be due to increased serum levels and altered composition of BAs post-SGx

The musculoskeletal side effects include muscle pain, muscle weakness, cramps and swelling in extremities including hands, arms, ankles, feet and/or lower legs