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Injection Volume: 15 L Temperature: Column: 3040 C, Autosampler: 48 C for stability

Rights and permissions About this article Cite this article Gobburu, J.V.S., Agers, H., Jusko, W.J

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Many tools have been developed and employed in the structural biology community to enhance the crystallizability of proteins, including in situ proteolysis 6,7,8 , lysine methylation 9,10,11 , surface entropy reduction 12,13,14 , metal mediated crystallization 15 , polymer-driven crystallization 16 , site-specific mutagenesis 17 , and chaperone-aided crystallization (also see recent reviews refs 18,19)