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Thats why people often notice early greying during periods of emotional strain, lifestyle imbalance, or post-illness recovery

After correction using the ComBat method ( Supplementary Figures 1C, D ), dataset differences among samples significantly decreased, and the clustering structure of RA and normal control groups in principal component space became clearer, indicating that the data processing workflow effectively enhanced data quality and the reliability of subsequent analyses

Barberine has also shown neuroprotective effects via elevating the mitochondrial membrane potential (MMP) (Moneim, 2015)