5.1.2 Enhancement of gut and bloodbrain barrier integrity Recent studies have shown that a vicious cycle of inflammation and oxidative stress is created at the renal level by the influx of uremic toxins and urea into the gastrointestinal lumen via the enterohepatic cycle, which exerts a selective pressure that encourages the excessive growth of bacterial species that produce urease, uricase, indole, and p-cresol-forming enzymes with a reduction in SCFAs-producing species (Vaziri et al., 2013
Anti-inflammatory and immune properties of polyunsaturated fatty acids (PUFAs) and their impact on colorectal cancer (CRC) prevention and treatment
Association Between Trimethylamine N-oxide Levels and CVD It is now widely accepted that plasma TMAO levels predict the risk of CVD, and TMAO levels have been proposed as a biomarker for assessing CVD risk
Finally, KlK4 and Klk2-ps , two peptidases that function in ECM degradation and remodeling, are also significantly increased in the Cebpb M epithelium as compared to WT, as is the GSEA pathway Tissue Remodeling (Fig 5A and B, Tables S2 and S3)