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Notably, in most countries PAC is freely sold as an OTC drug, raising the risk of unintentional abuse and increased adverse effects ( No answer can be given to the above open questions because PAC efficacy/adverse effects, unlike most of the drugs repositioned for COVID-19 therapy, have not yet been evaluated in controlled clinical trials or analyzed through retrospective analyses

Funding This study was supported by grants from the National Natural Science Foundation of China (82570731, 82170627), Basic-clinical integration innovation project of the Xian Jiaotong University (YXJLRH2022042, YXJLRH2022048), Key Research and Development Program of Shaanxi (2023-YBSF-350, 2024SF-YBXM-117) and Outstanding Youth Fund of Xian Jiaotong University (2022YQPY04), Institutional Foundation of The First Affiliated Hospital of Xian Jiaotong University (2021ZYTS-36, 2022MS-27)

La quantit de cystine rgit la vitesse et la quantit de GSH produite par lorganisme

In this study, RVX reduced testicular MDA and elevated GPx content, revealing that its anti-oxidant effect mediated its protection against testicular IR