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Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells

The wells were rinsed three times and a volume of 100 l of COS-7-OPH cell lysates containing 120 g protein was added and incubated at room temperature for 2 hours

248 By increasing intracellular NAD + concentrations, these compounds enhance SIRT1 activity, therefore supporting energy metabolism, reducing oxidative stress, and suppressing inflammation

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