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[116] First-trimester exposure to ondansetron has received particular attention in pregnancy safety research due to the critical nature of organ development during this period

The trials give a lot of details about common side effects

Interestingly, ALS and frontotemporal dementia (FTD) are closely related conditions and often share both genetic and disease mechanisms, especially in people with C9ORF72 mutations suggesting they may be part of the same disease spectrum (Parobkova and Matej, 2021)