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ROS-sensitive thioketal-linked polyphosphoester-doxorubicin conjugate for precise phototriggered locoregional chemotherapy

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Since nutrients have multiple roles throughout the body and are involved in multiple metabolic pathways, correction of nutritional deficiencies often yields systemic benefits.

It has been found that in many other organs and tissues, such as the dorsal root ganglion (GDR), the GPx is the first enzyme that is activated under high levels of EROS, indicating the importance of this enzyme as a first line of defense against stress oxidative [96, 97]