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Pregnancy and biologic treatment Overall, caution should be taken during treatment with biologics throughout pregnancy, with more data needed for many biologic treatments

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In mouse, HOXB1 maintains cardiac progenitors, as its depletion accelerates cardiac differentiation (Stefanovic et al, 2020)

It can also intravenously be used when a rapid onset of diuresis is desired as in acute pulmonary edema, or when gastrointestinal absorption is impaired or oral medication is not possible [1, 2]