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SKU: 19612693389
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Xiong Y, Mahmood A, Meng Y, Zhang Y, Zhang ZG, Morris DC, et al

The WNT inhibitor XAV939 enhances the expression of autophagy-related genes ATG5 and ATG7 in tubular epithelial cells by inhibiting -catenin nuclear translocation, thereby reducing TNF--induced M1 macrophage recruitment (157, 158)

552 Moreover, supplementation of NR can reduce the expression of neuroinflammation biomarkers in the spinal cord, alleviate the degeneration of motor neurons and appropriately extend the survival time of hSOD1G93A transgenic mice