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doi: 10.1097/HEP.0000000000000542

Additionally, there were no apparent changes in the concentration of fasting glucose of HbA1c across all treatment groups

In addition, specific metabolites such as endogenous adenine have been linked to kidney injury in experimental models and to diabetic kidney disease risk in patients, illustrating how metabolite biomarkers can nominate mechanistic pathways for intervention (Sharma et al., 2023