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Description

Genotype-phenotype correlations in sepiapterin reductase deficiency

doi: 10.1016/j.bpobgyn.2019.06.006 26 LaiZ

The reduction of GSSG to GSH is accompanied by the oxidation of NADPH to NADP+, leading to a decrease in absorbance at 340nm

It occurs naturally in human plasma, saliva, and urine, and its plasma concentration declines significantly with age, from approximately 200 ng/mL in young adults to much lower levels in older individuals