how does glutathione s-transferase cause drug resistance in cancer cells

how does glutathione s-transferase cause drug resistance in cancer cells transferases: substrates, inihibitors and pro-drugs and neurodegenerative diseases Frontiers | Modulation of redox

Name: how does glutathione s-transferase cause drug resistance in cancer cells transferases: substrates, inihibitors and pro-drugs and neurodegenerative diseases Frontiers | Modulation of redox
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Frontiers Modulation of redox homeostasis: A strategy to overcome cancer drug resistance how does glutathione s transferase cause drug resistance in cancer cells The Multifaceted Role of S Transferases Health and Disease Glutathione S transferases in kidney and System Xc GSH GPX4 axis: An important antioxidant system for the ferroptosis in drug resistant solid tumor therapy PMC Frontiers Multidrug Resistance in Cancer: Understanding Molecular Mechanisms, Immunoprevention and Therapeutic Approaches

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doi: 10.1016/j.cmet.2005.01.003 40

However, in contrast, patients with COVID-19 was shown to have reduced BHB concentrations, indicating that this virus may impair infection-induced ketogenesis (88)

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Soluble GSTs consist of two subunits (25 kDa), which are divided into two domains: the N-terminal / forming the G region and the -helical forming most of the H region, which is responsible for the binding of the electrophilic substrate