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Still, the poster child is the arctic ground squirrel ( The basic idea of utilizing supercooling in the transplantation field goes back at least to the 1960s ( O -methyl glucose (3-OMG) ( polyethylene glycol (PEG) have allowed transplantations with success at 3 days, with 4 days supercooled storage possible but a reduction in survival ( As supercooling is not an asymptotically stable state by thermodynamic standards, it is often assumed that there is a significant risk of ice formation in the organ over the durations of storage practical for transplantation

Human aging, infections, poisoning, exogenous toxins, oxidative stress, electrophilic compound attack can be made within the cell plasma GSH level reduces, the phenomenon of apoptosis occurs in very early stage, its degradation process can be observed in the early apoptosis, so it can be observed in the early stage of apoptosis

Hydrogen peroxide is mainly neutralized by the enzyme catalase, which turns hydrogen peroxide into water and oxygen, and the tripeptide glutathione (GSH), which converts hydrogen peroxide into water through a reducing reaction catalyzed by the enzyme glutathione peroxidase (GPX)