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The aberrant neurotransmission is associated with several structural and functional changes in the brain and other encephalic structures, as it has been observed that patients with BD display abnormalities in neural circuitries supporting emotion processing, emotion regulation and reward processing [36]

Severe intrahepatic cholestasis of pregnancy is a risk factor for preeclampsia in singleton and twin pregnancies

VcGSTF128) subfamilies were the most abundant, together constituting over half of all VcGSTs, with the tau subfamily being the largest as commonly observed in higher plants

However, it is now recognized that development and progression of AD is likely due to multiple etiologies, and there is increasing evidence implicating oxidative stress (OS) as an early event in the trajectory of MCI and AD [2, 18, 75]