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halothane) increase cardiac automatic irritability and therefore seem to sensitize the myocardium to the action of intravenously administered epinephrine or norepinephrine, resulting in an increased incidence of cardiac arrhythmias Norepinephrine should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or tricyclic antidepressants , because severe, prolonged hypertension may result Notes: Another synonym for noreinephrine is

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Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia

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