glutathione-s-transferase conjugated p53 Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression Frontiers | Glutathione S-Transferase Enzymes

The pipette solution for whole-cell recordings was modified to include an intracellular dye (Alexa Fluor 350 hydrazide dye) and contained: 120 mM K-gluconate, 10 mM KCl, 10 mM HEPES, 5 mM EGTA, 1 mM CaCl 2 , 1 mM MgCl 2 and 2 mM MgATP, and 0.03 mM Alexa Fluor 350 hydrazide dye (pH 7.3)

PMID 21906675

Although compensatory mechanisms attempt to counteract these harmful effects, prolonged astrocyte activation often leads to irreversible pathological conditions, tipping the balance toward neuronal degeneration (Fig

Herein, we summarise and discuss current information on the role of glycometabolic enzymes in promoting glucose metabolism and MDR in tumor cells (Figure 2), and conclude the molecular mechanisms by which glycometabolic enzymes promote MDR in tumor cells (Table 1)