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Several clinical trials have assessed the efficacy of systemic delivery of recombinant IGF-I in patients who could benefit from strength gains, summarized in Table 1

First-in-human trial of M9140, an anti-CEACAM5 antibody drug conjugate (ADC) with exatecan payload, in patients (pts) with metastatic colorectal cancer (mCRC)

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for failing to maintain written quality control procedures, which constitutes a violation of current Good Manufacturing Practices (cGMP) and caused the companys products to be declared adulterated