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Recombinant hCG was found to be more potent than LH in both HEK293 and mouse Leydig tumour cells, demonstrating that LH and hCG display biased agonism at their shared receptor

In: Papageorgiou GC, Govindjee, editors

The regulatory effect of GPX8 on Ca 2+ may be related to the inositol 1,4,5-triphosphate receptor (IP3R) effect, and the transmembrane domain (TMD) of GPX8 is thought to play a key role in the regulation of Ca 2+ signaling (Yoboue et al., 2017)

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