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A SNP associated with higher activity is detrimental because it inhibits serotonin at a lower threshold

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References [1] 10.3389/fphar.2022.1026182 [2] 10.3390/ph18020185 [3] 10.3389/fendo.2021.767785 [4] 10.1016/S0014-2999(97)01033-9 [5] 10.1196/annals.1415.004 [6] 10.2147/DDDT.S82030 [7] 10.3389/fmolb.2022.925700 [8] 10.18632/oncotarget.11168 [9] 10.1016/j.bmcl.2014.12.029 [10] 10.3390/biomedicines10112696