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Intramuscular injections are generally inconvenient due to pain and require healthcare professionals for administration, thus increasing the economic burden on patients which ultimately leads to discontinuation of the treatment

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In fact, the number of ferritin deficiencies was comparable between all groups, ranging from 7 to 16% at 2 years and from 10 to 13% at 3 years of follow-up, which is lower than reported in previous literature (1759% at 24 years after SG) [8, 9, 20, 23,24,25]