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342 However, the damaged mitophagy leads to ROS accumulation, inflammasome activation, and lipid accumulation, which results in cell damage

Furthermore, longitudinal change in GSH mPFC (i.e., the difference between baseline and 6 months of NAC/placebo add-on treatment) correlates with the change in gFA along the fornix bundle in NAC patients and in NAC and placebo patients pooled together

A diagnosis of severe AUD conferred an age-dependent increased risk for ALD, with highest impact in those 70: HR 4.01, 95%CI 2.71-5.93, p 70 years: HR 0.12, CI 0.02-0.97, p=0.046), but not in patients 10d

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